Tacrus 0.1% Ointment - (Tacrolimus Monohydrate 0.1%)


Tacrolimus 0.1% Ointment contains tacrolimus, a macrolide immunosuppressant produced by Streptomyces tsukubaensis. It is for topical dermatologic use only. Tacrolimus has an empirical formula of C44H69NO12•H2O and a formula weight of 822.03. Each gram of Tacrolimus Ointment contains (w/w) 0.1% of tacrolimus in a base of mineral oil, paraffin, propylene carbonate, white petrolatum and white wax. Tacrolimus ointment was developed specifically for the treatment of atopic dermatitis and represents the first in a new class of topical, nonsteroidal immunomodulators. The proposed indication for tacrolimus ointment 0.1% is primary therapy for the short-term and long-term treatment of the signs and symptoms of atopic dermatitis in adult and pediatric patients 2 years of age or older.

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